Epilepsy Sparks Insights

Understanding Acute Symptomatic Seizures: A Deep Dive - Clio Rubinos

What are Acute Symptomatic Seizures, how do they differ from epileptic seizures, and how can one recover? Who will develop an epilepsy after one and what are the causes?! Think stroke, TBI, tumours, infection, encephalitis, status epilepticus...! Find out all about it from neurocritical care and epileptology specialist neurologist Clio Rubinos.
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Website, transcript, & more about Clio: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/clio-rubinos-acute-symptomatic-seizures
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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Exploring the Future of Brain Imaging: OPM-MEG - Zelekha Seedat

Post-doc researcher Zelekha Seedat discusses her work as a postdoctoral researcher at Young Epilepsy, focusing on Magnetoencephalography (MEG) and the innovative Optically Pumped Magnetometers (OPM) technology. She explains the differences between MEG and EEG, the advantages of OPM technology, and the challenges faced in interpreting data. The conversation also covers the importance of combining EEG with OPM-MEG for better data accuracy, the future potential of OPM-MEG in clinical settings, and how to get involved in her research!
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🔗 Website & more about Zelekha 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/zelekha-seedat-opm-meg-young-epilepsy 
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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OPM-MEGs - New, Precise Brain Scans For Epilepsy - Christine Embury

Post-doc researcher Christine Embury shares with us her research on the cool OPM-MEG technology for brain imaging - its advantages (particularly for children with refractory epilepsy and considering brain surgery!) and how it could improve patient outcomes and our understanding of developmental trajectories in paediatric epilepsies!  Lastly, Christine and Torie chat about the cost-effectiveness of the device, its benefits from an energy usage/climate change perspective, and how both patients and clinicians can get involved in the research!
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🔗 Transcript & more about Christine 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/christine-embury-opm-meg-young-epilepsy 
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇 https://www.epilepsysparks.com/glossary 
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Improving Epilepsy Care For Children in Iran - Reza Shervin-Badv

Reza Shervin-Badv, a paediatric epileptologist and neurologist talks about the diverse care available for people in Iran, plus the common epilepsy stigma which is being challenged through education and advances in medical care.
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🔗 Website & more about Reza: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/reza-shervin-badv-iran-epilepsy-stigma
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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New "Master-Controller" Molecule in Epilesy! - Mona Heiland

Find out about a new epilepsy discovery; how the microRNA-335 molecule impacts people with both Dravet Syndrome and Temporal Lobe Epilepsy, and what this could mean for research going forward! All with post-doc researcher Mona Heiland!
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🔗 Website & more about Mona: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/mona-heiland-newly-discovered-molecule-microrna-335
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Chapters 📖
00:00 Trailer & Intro
00:45 Meet Mona
01:07 Explaining Sodium Channel Epilepsies
06:03 Understanding MicroRNAs and Their Role in Epilepsy
07:47 Research Findings on MicroRNA-335 and Sodium Channels
10:01 Future Directions in Precision Therapies for Epilepsy
11:18 Conclusion & thanks
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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Decreasing Language Decline Caused by Epilepsy Surgery - Sjoerd Vos

Physicist Sjoerd Vos shares his research in neuroimaging; aiming at decreasing language decline caused by temporal lobe resections!
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🔗 Website & more about Sjoerd
https://www.torierobinson.com/epilepsy-sparks-insights/sjoerd-vos-physics-mri-temporal-lobe-epilepsy-resection-cognitive
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇 https://www.epilepsysparks.com/glossary 
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The Power of Collaboration in Epilepsy Research - Eduardo Pérez Palma

Eduardo Pérez Palma, a neurogenetics scientist and bioinformatician, discusses his work in neurogenetics and epilepsy research, emphasising the importance global collaboration in studying the epilepsies in different parts of the world! Eduardo also shares the upcoming Latin American Congress on Genetic Epilepsiesin Jan 2025; which aims to bring together experts from various fields to share knowledge and perspectives!
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🔗 Website & more about Eduardo: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/eduardo-perez-palma-neurogenetics-dee-latin-america 
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Chapters 📖
- Intro to Eduardo
- The Value of Genetic Testing in Epilepsy
- Diversity and Representation in Genetic Research
- Understanding Developmental Epileptic Encephalopathies (DEEs)
- Contributing to Epilepsy Research
- Latin American Congress on Epileptsy Genetics
- Conclusion & thanks
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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#genetics #neurogenetics #exomesequencing #epilepsy

Advancements in Stem Cell Research for Drug-Resistant Epilepsy - Patrick Kwan

Learn of exciting research into a drug screening platform for personalised medicine for the epilepsies - through adult neurologist and researcher Patrick Kwan; head of the Kwan Lab! Patrick describes the process of extracting stem cells from blood, culturing them, and using them to develop new treatments for drug-resistant epilepsy. The conversation highlights the importance of collaboration and data sharing in epilepsy research.
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🔗 Website & more about Patrick👇
https://www.torierobinson.com/epilepsy-sparks-insights/patrick-kwan-advances-stem-cell-research-epilepsy
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇 https://www.epilepsysparks.com/glossary 
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Using Viral Vectors To Stop Epilepsy - José M Serratosa

People with an epilepsy might be nervous about getting "gene therapy" - but in today's mini-episode, in part 2 of 2, epileptologist José M Serratosa is asked if he would get gene therapy and why(!), explains the use of viral vectors for treating genetic epilepsies, where we are in preclinical development, what is next, and what is also holding us back!
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🔗 Transcription & more about José: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/jose-m-serratosa-gene-therapies-viral-vectors 
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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#epilepsy #genetherapy #genetics #vectors #viralvectors #lafora 

Gene Therapy: A Promising Approach for The Epilepsies? - José M Serratosa

What does the future for epilepsy treatments hold?! Epileptologist José M Serratosa shares his predictions for epilepsy gene therapies; highlighting the importance of addressing all symptoms - including cognitive, motor, and psychiatric - as well as the seizures. Jose explains the role of viral vectors and how they may save people! This is part 1 of 2 with José - in part 2, the conversation goes into the challenges of research clinical trials for these therapies; from basic, to pre-clinical, to clinical!
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🔗 Transcription & more about José: 👇🏻
https://www.torierobinson.com/epilepsy-sparks-insights/jose-m-serratosa-future-epilepsy-gene-therapies 
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Don’t understand all the terms used? Check out the Epilepsy Sparks Glossary! 👇🏻 https://www.epilepsysparks.com/glossary 
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#epilepsy #genetherapy #genetics #vectors #viralvectors #lafora